This package has been designed to help understand whether your molecule is fit for purpose by generating a predicted hepatic clearance, volume of distribution and half-life. These parameters are essential to determine during an early stage drug screening cascade.
Description of Service
Predicted clearance, distribution and half-life in pre-clinical species and/or man using GastroPlus™
- Blood:plasma ratio, Hepatocyte CLint, PPB (for each species)
XenoGesis will generate a written report together with a simulated concentration-time profile from 1mg/kg IV bolus dose for each species.